Celgene Corporation
Dec 9, 2015
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Abstracts at San Antonio Breast Cancer Symposium Highlight ABRAXANE® as a Potential Backbone Therapy in Neoadjuvant and Triple-Negative-Breast Cancer

SUMMIT, N.J.--(BUSINESS WIRE)-- Celgene Corporation (NASDAQ:CELG) today announced that multiple studies being presented at the San Antonio Breast Cancer Symposium will highlight the investigational use of ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) as neoadjuvant therapy in high-risk early breast cancer and in combination with a platinum in triple-negative breast cancer. Additionally, studies will evaluate ABRAXANE as a potential backbone of therapy with new immune-oncology agents.

"The studies being presented at the San Antonio Breast Cancer Symposium this year support continued research into ABRAXANE as a taxane to combine with other agents in triple-negative breast cancer in both early and metastatic disease," said Jacqualyn A. Fouse, Ph.D., President, Hematology/Oncology for Celgene. "Our research efforts in this disease area underscore our ongoing commitment to patients who have few new therapeutic options."

Studies being presented include:

To view all abstracts for studies being presented at the San Antonio Breast Cancer Symposium, visit http://www.abstracts2view.com/sabcs15/

ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension)(albumin-bound) is indicated for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Prior therapy should have included an anthracycline unless clinically contraindicated.

Important Safety Information

WARNING - NEUTROPENIA

CONTRAINDICATIONS

Neutrophil Counts

Hypersensitivity

WARNINGS AND PRECAUTIONS

Hematologic Effects

Nervous System

Hypersensitivity

Hepatic Impairment

Albumin (Human)

Use in Pregnancy: Pregnancy Category D

Use in Men

ADVERSE REACTIONS

Randomized Metastatic Breast Cancer (MBC) Study

Postmarketing Experience With ABRAXANE and Other Paclitaxel Formulations

DRUG INTERACTIONS

USE IN SPECIFIC POPULATIONS

Nursing Mothers

Pediatric

Geriatric

Renal Impairment

DOSAGE AND ADMINISTRATION

Please see full Prescribing Information, including Boxed WARNING.

About Celgene

Celgene Corporation, headquartered in Summit, New Jersey, is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of innovative therapies for the treatment of cancer and inflammatory diseases through gene and protein regulation. For more information, please visit www.celgene.com. Follow us on Twitter @Celgene, and on Facebook, Pinterest and LinkedIn.

Forward-Looking Statements

This press release contains forward-looking statements, which are generally statements that are not historical facts. Forward-looking statements can be identified by the words "expects," "anticipates," "believes," "intends," "estimates," "plans," "will," "outlook" and similar expressions. Forward-looking statements are based on management's current plans, estimates, assumptions and projections, and speak only as of the date they are made. We undertake no obligation to update any forward-looking statement in light of new information or future events, except as otherwise required by law. Forward-looking statements involve inherent risks and uncertainties, most of which are difficult to predict and are generally beyond our control. Actual results or outcomes may differ materially from those implied by the forward-looking statements as a result of the impact of a number of factors, many of which are discussed in more detail in our Annual Report on Form 10-K and our other reports filed with the Securities and Exchange Commission.

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Source: Celgene Corporation

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